Integration of Copy Number and Methylation Data Identified from the Illumina® Infinium HumanMethylation450 BeadChip Array
Integration of genomic data and epigenomic data as a means for understanding complex genomic regulatory mechanisms is gaining in popularity. In this webinar, we will show you how to use Partek® Genomics Suite® to identify copy number regions from the Illumina® Infinium HumanMethylation450 BeadChip array and merge the results with differentially methylated regions detected using the same arrays.
Import Illumina .idat files and normalize the data
Detect differentially methylated regions
Remove probes with SNP in the vicinity of the query site
Visualize the methylation signature
Create a list of genes regulated by differential methylation
Identify copy number regions
Find copy number regions shared across study samples
Integrate the copy number data with methylation data
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