Integration of Copy Number and Methylation Data from the Illumina® Infinium HumanMethylation450 BeadChip Array

Integration of Copy Number and Methylation Data from the Illumina<sup>®</sup> Infinium HumanMethylation450 BeadChip Array

Integration of Copy Number and Methylation Data from the Illumina® Infinium HumanMethylation450 BeadChip Array

Integration of genomic data and epigenomic data as a means for understanding complex genomic regulatory mechanisms is gaining in popularity. In this webinar, we will show you how to use Partek® Genomics Suite® to identify copy number regions from the Illumina® Infinium HumanMethylation450 BeadChip array and merge the results with differentially methylated regions detected using the same arrays.

Learn how to:

  • Import Illumina .idat files and normalize the data
  • Detect differentially methylated regions
  • Remove probes with SNP in the vicinity of the query site
  • Visualize the methylation signature
  • Create a list of genes regulated by differential methylation
  • Identify copy number regions
  • Find copy number regions shared across study samples
  • Integrate the copy number data with methylation data

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Kathi GoscheIntegration of Copy Number and Methylation Data from the Illumina® Infinium HumanMethylation450 BeadChip Array