Integrated Genomics

Find Interesting Genes through Multiple Experimental Approaches and Common Annotation Problems

Functional Genomics, systems biology and even comparative genomics, turn concrete within Partek Genomics Suite (Partek GS).

Cell biology today benefit from high-throughput technologies like microarrays, next generation sequencing, proteomics & metabolomics technologies. These technologies cater several assays such as gene expression, alternative splicing, copy number, miRNA, SNP, ChIP, methylation etc.

To offer a more complete picture of the biology, Partek is standardizing ways to manage various data formats, to compute integrative statistics, visualize the results interactively while appending biological annotations and inferring function - when dealing with more than one assay or technology. Systems biology is bioinformatics. Large-scale and high throughput analysis of biological systems help address important biological problems such as fighting disease, protecting plant life and harnessing nature’s technology.

Partek GS will integrate platforms and offer data mining algorithms using the genome as the scaffold. The power of extending your hypothesis beyond expression profiling, with regulatory networks and DNA sequence variations is at your fingertips. The integration workflows in Partek GS will make your task easy. Try Partek Genomics Suite for your integrated genomics data.

Specific Applications for Integrated Genomics in Partek Genomics Suite

RNA-Seq & Exon microarray

Within Partek GS, view your existing microarray data side by side with your next-generation RNA-Seq data. The predicted patterns of transcript abundance from RNA-Seq can often assist with interpreting exon data. Lower your target validation costs by running two genomic level discovery assays.

Gene Expression & ChIP-Seq

Once transcription sites are identified, a natural step is to query if a specific binding event affects changes in nearby mRNAs. A combination of hybrid data tables between ChIP-Seq and gene expression coupled with integrated visualization allows you to interrogate for genes with both a regulation event as well as a change in the mRNA abundance. Find the instances where regulation patterns affect gene expression levels.

Gene Expression & Copy Number

Partek GS offers four different methods to integrate copy number and gene expression results. All of the integrated analysis methods lead to integrated genomic visualization. Identify expression changes controlled by both phenotype and copy number.